They have decided not to sign a new record deal and will bow out with a farewell tour in December - five years after finding mainstream success through The X Factor.
Aston said: "It's just that time. We are still best of friends and always will be, but this is the end.
"The question was asked, 'Can you do this together for another five or so years? Can you see that happening?' Between the four of us, there was no definite 'Yes' in the room. We had to dig deep and find the right solution.
"We haven't fallen out. We leave with some amazing successes under our belt, and we can say goodbye in style."
Marvin added: "It's an emotional time. There's no getting away from that. We have been through so much together. But we have to be mature and look at this decision as a celebration of what we managed to achieve.
"We wanted to finish on a high. We're finishing with an arena tour - our third arena tour - and that is a massive achievement. The last 5 or so years have been nothing short of incredible. It has been an incredible journey."
JLS rose to fame after finishing in second place to Alexandra Burke on The X Factor in 2008. The group have topped the UK singles chart on five occasions, have sold over ten million records and are multiple Mobo and Brit Awards winners.
JB Gill added that the group will honour their commitments to charitable organisation the JLS Foundation.
"We've all made a commitment on paper that no matter what we're doing, wherever we are, whatever happens from here on, we will commit to the Foundation," he said. "We're already in a partnership with Cancer Research UK - we're committed to them for two years, and we want to raise £2 million."